Alector was founded to explore two scientific insights: that the immune system plays a critical role in neurodegenerative diseases, and that redirecting aberrant immune cell activity in the brain could improve healthy function. Our strategy is conceptionally similar to immuno-oncology. Immuno-oncology therapies recruit the peripheral adaptive immune system to counteract tumors. Our immuno-neurology therapies recruit the central innate immune system to counteract brain pathologies.
Combining expertise in human genetics, immunology, and neurology, our fierce curiosity drives us to gain deeper understanding into the biologic underpinnings of the diseases we aim to treat so we can identify new medicines with the potential to profoundly impact patients’ lives.